Adjuvant corticosteroid therapy in hepatosplenic candidiasis-related IRIS
نویسندگان
چکیده
منابع مشابه
Adjuvant Corticosteroid Therapy in Hepatosplenic Candidiasis-Related Iris
Candida infections are the most frequent infections in neutropenic patients. Hepatosplenic candidiasis (HSC) is a part of disseminated Candida infection that occurs most commonly in patients with hematologic malignancies treated with chemotherapy and requires protracted antifungal therapy. During invasive mycosis with rapid resolution of immunosuppression, immune reconstitution inflammatory syn...
متن کاملAdjuvant corticosteroid therapy for chronic disseminated candidiasis.
BACKGROUND Chronic disseminated candidiasis (CDC) is typically observed during neutrophil recovery in patients with acute leukemia and requires protracted antifungal therapy. OBJECTIVE Our objective was to document the efficacy and tolerance of corticosteroid therapy (CST) in patients with symptomatic CDC, including those who experienced fever and abdominal pain despite ongoing antifungal the...
متن کاملHepatosplenic candidiasis in patients with acute leukaemia.
A retrospective study of 23 patients with acute leukaemia and hepatosplenic candidiasis (HSC) was conducted to evaluate clinical treatment characteristics in terms of amount and duration of antifungal agents and to assess treatment outcome. Patients were admitted to two major tertiary care centres between 1990 and 1998. The diagnosis of HSC was based on clinical, blood cultures, histologic and ...
متن کاملHepatosplenic candidiasis--a contraindication to marrow transplantation?
To determine whether a prior history of hepatosplenic candidiasis resulted in increased Candida-associated morbidity and mortality after marrow transplant, 15 consecutive patients with biopsy-proven hepatosplenic candidiasis were observed prospectively. All patients received amphotericin B before transplant. Amphotericin B was continued at a dose of 0.5 mg/kg/day from conditioning through marro...
متن کاملHepatosplenic candidiasis: successful treatment with fluconazole.
PURPOSE To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment. PATIENTS AND METHODS Six patients (ages 3 to 44) with acute leukemia and hepatosplenic candidiasis who did not respond to prior antifungal therapy were treated with fluconazole. RESULTS All six patients had fever and three had nausea a...
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ژورنال
عنوان ژورنال: Mediterranean Journal of Hematology and Infectious Diseases
سال: 2012
ISSN: 2035-3006
DOI: 10.4084/mjhid.2012.018